Turquoise Eyes: A Novel about Problem Solving & Critical Thinking

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Some genes play a major role in determining eye color, while others only have a small contribution. Muichiro is one of only four Hashira that use a normal Nichirin Katana. The other three are Kyojuro Rengoku, Sanemi Shinazugawa, and Giyu Tomioka.

Menon IA, Basu PK, Persad S, Avaria M, Felix CC, Kalyanaraman B (1987). "Is there any difference in the photobiological properties of melanins isolated from human blue and brown eyes?". Br J Ophthalmol. 71 (7): 549–52. doi: 10.1136/bjo.71.7.549. PMC 1041224. PMID 2820463. Fan S, Dyer CR, Hubbard L. Quantification and Correction of Iris Color." Technical report 1495, University of Wisconsin–Madison, Dec 2003. Grigore M, Avram A. Iris colour classification scales—then and now. Rom J Ophthalmol. 2015;59(1):29-33.In 2011, Kunis revealed that the condition left her blind in the affected eye for many years and required cataract surgery to replace the damaged lens. The procedure restored her vision and her original eye color, which now matches her other eye. Max Scherzer Only 2% of the world's population have green eyes, making it the rarest eye color. Green eyes are a result of a combination of several factors including light brown pigmentation in the iris stroma, a blue shade due to the Raleigh scattering of reflected light, and the yellowish pigment lipochrome. Green eyes are common in Europe's Central, Western, and Northern regions. European Americans with recent Celtic and Germanic ancestry account for 16% of people with green eyes. Gray Eyes - 3% Gray is the second-rarest natural eye color. A number of other genes play smaller roles in eye color. The roles of the genes ASIP, IRF4, SLC24A4, SLC24A5, SLC45A2, TPCN2, TYR, and TYRP1 are thought to combine with those of OCA2 and HERC2. Eye color inheritance pattern Hammond BR, Fuld K, Snodderly DM (1996). "Iris color and macular pigment optical density". Exp. Eye Res. 62 (3): 293–7. doi: 10.1006/exer.1996.0035. PMID 8690039. Bright Red Nichirin Sword: During his battle against Kokushibo, Muichiro dyed his Nichirin Sword a bright red color by gripping it with all his might, allowing him to hamper the regeneration of Kokushibo, which later proved to play a pivotal role in his defeat. [16]

Third Form: Scattering Mist Splash ( 参 ( さん ) ノ 型 ( かた ) 霞 ( か ) 散 ( さん ) の 飛 ( し ) 沫 ( ぶき ) , San no kata: Kasan no Shibuki ?) [33] - The user performs a powerful and swift circular slash that can blow away incoming projectiles. Wielgus AR, Sarna T (2005). "Melanin in human irides of different color and age of donors". Pigment Cell Res. 18 (6): 454–64. doi: 10.1111/j.1600-0749.2005.00268.x. PMID 16280011. Violet eyes are even rarer, but they’re a bit misleading; someone with “violet” irises is usually sporting a special shade of blue. Light bounces off their surroundings and turns their eyes into a deceiving, yet breathtaking rendition of purple.Approximately 8% to 10% of the global population have blue eyes. [25] A 2002 study found that the prevalence of blue eye color among the white population in the United States to be 33.8% for those born from 1936 through 1951, compared with 57.4% for those born from 1899 through 1905. [14] As of 2006 [update], one out of every six Americans, or 16.6% of the total US population, has blue eyes, [60] including 22.3% of whites. The incidence of blue eyes continues to decline among American children. [61] Of Slovenes, 56% have blue/green eyes. [62] In Spain, the iris color distribution among the population is 16.3% blue-gray, 55.2% green-hazel, and 28.5% brown. [63] Gray Gray eyes Frost: Why Do Europeans Have So Many Hair and Eye Colors?". cogweb.ucla.edu . Retrieved 27 February 2018. Hawkins TA, Stewart WC, McMillan TA, Gwynn DR (1994). "Analysis of diode, argon, and Nd: YAG peripheral iridectomy in cadaver eyes". Doc Ophthalmol. 87 (4): 367–76. doi: 10.1007/BF01203345. PMID 7851220. S2CID 30893783.

The other main gene involved is called HERC2. Intron 86 on this gene controls the expression of OCA2, activating it or deactivating it as required. At least one polymorphism in this intron reduces the expression and activity of OCA2,which reduces how much P protein is produced. Cumming RG, Mitchell P, Lim R (2000). "Iris color and cataract: The Blue Mountains Eye Study". American Journal of Ophthalmology. 130 (2): 237–238. doi: 10.1016/S0002-9394(00)00479-7. PMID 11004303.It is the most popular souvenir sold in various forms. Instantly recognisable by its blue, white, and turquoise circles, locals in some places still use it culturally and give at weddings and births. In contrast, others brush it off as pure superstition and use it for symbolic décor or aesthetic purposes only. But what is the meaning and history behind it, and is it worth wearing one? Changes (lightening or darkening) of eye color during early childhood, puberty, pregnancy, and sometimes after serious trauma (like heterochromia) suggest that eyes sometimes change color under certain circumstances, due to chemical reactions or hormonal changes within the body. Some people may group gray eyes (also spelled grey eyes) with blue eyes. Their low melanin content is similar, but in fact, gray irises are significantly more rare than standard blue eyes. Imesch PD, Wallow IH, Albert DM (1997). "The color of the human eye: a review of morphologic correlates and of some conditions that affect iridial pigmentation". Surv Ophthalmol. 41 (Suppl 2): S117–23. doi: 10.1016/S0039-6257(97)80018-5. PMID 9154287. Two factors affect the color of one’s eyes: the pigmentation of the eye’s iris and the frequency of light scattering by the murky medium in the iris stroma. In humans, this pigmentation of the iris depends on the melanin concentration in the iris pigment epithelium, it's content within the iris stroma, as well as the cellular density of the stroma. The more melanin concentration one has, the darker one’s eyes will be. Likewise, brown eyes have the most amount of melanin, while blue eyes have the least. Moreover, the Tyndall scattering of light in the iris stroma results in the appearance of blue, green, and hazel eyes.

Eiberg, Hans; Troelsen, Jesper; Nielsen, Mette; Mikkelsen, Annemette; Mengel-From, Jonas; Kjaer, Klaus W.; Hansen, Lars (2008). "Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression". Hum. Genet. 123 (2): 177–87. doi: 10.1007/s00439-007-0460-x. PMID 18172690. S2CID 9886658. Muiños Díaz, Yerena; Saornil, Maria A.; Almaraz, Ana; Muñoz-Moreno, Mari F.; García, Ciro; Sanz, Ruperto (2009). "Iris color: validation of a new classification and distribution in a Spanish population-based sample". European Journal of Ophthalmology. 19 (4): 686–689. doi: 10.1177/112067210901900427. ISSN 1120-6721. PMID 19551689. The inheritance pattern followed by blue eyes was previously assumed to be a mendelian recessive trait, however, eye color inheritance is now recognized as a polygenic trait, meaning that it is controlled by the interactions of several genes. [52] Depending on the inflammation, those with this condition can experience the iris lightening or darkening. Your eyes may also turn hazel due to this condition.Although there are rare cases of individuals with different eye color variations, such as heterochromia (two different colored eyes) or sectoral heterochromia (one eye with multiple colors), turquoise eyes, specifically, are not considered a naturally occurring eye color. Why?